Heneicosapentaenoic acid

By Targets:	Biochemical Assay Reagents (1) Isotope-Labeled Compounds (1)
By Research Areas:	Cardiovascular Disease (1) Neurological Disease (1)

Targets Recommended: Amino Acid Derivatives Free Fatty Acid Receptor Fatty Acid Synthase (FASN) Apical Sodium-Dependent Bile Acid Transporter G protein-coupled Bile Acid Receptor 1

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N7833

*(all-Z)-6,9,12,15,18-Heneicosapentaenoic* Acid** Heneicosapentaenoic acid	Biochemical Assay Reagents	Others
Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.

HY-141469

*6,9,12,15,18-Heneicosapentaenoic* acid** HPA; Heneicosapentaenoic acid methyl ester	Others	Cardiovascular Disease Neurological Disease
6,9,12,15,18-Heneicosapentaenoic acid (HPA; Heneicosapentaenoic acid methyl ester) inhibits the conversion of α-linoleic acid into Arachidonic acid (HY-109590) in hepatoma cells, the activation of prostaglandin H synthase and thromboxane synthesis in isolated platelets. 6,9,12,15,18-Heneicosapentaenoic acid is weak inducer of acyl-CoA oxidase in hepatoma cells .

HY-N7833S

Heneicosapentaenoic acid-d6

Isotope-Labeled Compounds Others

Heneicosapentaenoic acid-d₆ is the deuterium labeled Heneicosapentaenoic acid[1].

Heneicosapentaenoic acid-d6	Isotope-Labeled Compounds	Others
Heneicosapentaenoic acid-d₆ is the deuterium labeled Heneicosapentaenoic acid[1].

Cat. No.	Product Name	Type

HY-N7833

*(all-Z)-6,9,12,15,18-Heneicosapentaenoic* Acid** Heneicosapentaenoic acid	Biochemical Assay Reagents
Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.

(all-Z)-6,9,12,15,18-Heneicosapentaenoic Acid

Heneicosapentaenoic acid

Biochemical Assay Reagents

Heneicosapentaenoic Acid (HPA) is a 21:5 omega-3 fatty acid found in trace amounts in the green alga B. pennata and in fish oils. Its chemical composition is similar to eicosapentaenoic acid (EPA), except that a carbon is extended at the carboxy terminus, placing the first double bond at the δ6 position. HPA can be used to study the importance of double bond position in omega-3 fatty acids. It incorporates phospholipids and triacylglycerols in vivo with the same efficiency as EPA and docosahexaenoic acid, and exhibits a strong inhibitory effect on the synthesis of arachidonic acid from linoleic acid. HPA is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but retains the ability to rapidly inactivate PGHS.

Cat. No.	Product Name	Chemical Structure

HY-N7833S

Heneicosapentaenoic acid-d6

Heneicosapentaenoic acid-d₆ is the deuterium labeled Heneicosapentaenoic acid[1].

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社
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Inhibitors & Agonists

Biochemical Assay Reagents

Isotope-Labeled Compounds